omicverse.micro.Beta

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omicverse.micro.Beta#

omicverse.micro.Beta(adata: ad.AnnData, rarefy_depth: int | None = None, seed: int = 0)[source]#

Compute sample × sample distance matrices.

Parameters:

  • adata – Samples × features AnnData with int counts.

  • rarefy_depth (default: None) – If set, subsample to this depth before distance calculation (good practice for Bray-Curtis / Jaccard to remove library-size effects). None → use raw counts.

  • seed (default: 0) – Random seed for rarefaction.

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