omicverse.bulk.batch_correction

omicverse.bulk.batch_correction#

omicverse.bulk.batch_correction(adata, batch_key=None, key_added='batch_correction')[source]#

Perform batch effect correction using ComBat algorithm.

Parameters:

  • adata (AnnData) – AnnData object containing expression data.

  • batch_key (default: None) – Key in adata.obs containing batch information.

  • key_added (str (default: 'batch_correction')) – Name for the corrected data layer. Default: ‘batch_correction’.

Returns:

The function modifies adata.layers[key_added] in place with batch-corrected expression data.

Return type:

None

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